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Lipids, lipophilic actives, pharmaceitucals

Encapsulation helps stabilises lipid emulsions against physical and chemical instabilities. At the same time, bioavailability is increased. A crossover clinical trial conducted with healthy adults showed that DHA and EPA absorption, as measured in blood plasma, was higher (by 50%) in individuals fed encapsulated Omega-3. It is suggested that the encapsulated lipids are able to transit through the stomach intact and the mucoadhesive microgels adheres to the mucosa in the intestines and releases the lipid nanoemulsion for rapid absorption.